An overview of Pre-Implantation Genetic Diagnosis

   2019-05-23       111        Health
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Earlier a very interesting success story which belongs to Mrs. B was shared in our blogs. She visited at the Indo Nippon IVF and consulted the doctors here for the IVF procedure, but all was in vain.

Earlier a very interesting success story which belongs to Mrs. B was shared in our blogs. She visited at the Indo Nippon IVF and consulted the doctors here for the IVF procedure, but all was in vain. For the complete team, this case was a great challenge. She went for the IVF procedure many times but every time, after she conceives, preterm delivery is the result and the babies are not able to survive. A couple of fresh embryo transfers are attempted in a surrogate using her cryopreserved Blast ocysts. The conception was positive but later, congenital defects were detected in her anomaly scan leading to a miscarriage.

The couple has completely lost hope of having their own child. Now, the Indo Nippon IVF has other thoughts, they decided to find the root cause creating this problem. They learned that there were some anomalies in the report of the wife after doing Karyotyping on the couple. Finding this, they do conduct a Pre-Implantation Genetic Diagnosis on Day 5 cryopreserved embryos. The process allowed isolating a single normal blastocyst, which was then implanted in the surrogate. The process was a huge success and it led to the birth of a beautiful and healthy baby girl. You can witness that the Pre-Implantation Genetic Diagnosis famously known as PGD have a big part to play in the success story of Mrs. B. Now, it’s our absolute duty to let you know more about this brilliant technology.

is referred to one or both parents when they are known to have some kind of genetic abnormality. The testing on an embryo is then performed to check out that if it carries the same genetic abnormality or not. The cures of most of the genetic conditions do not exist and we are not sure whether they will exist at all. For the available treatments too, there are some risks of adverse effects which we have to take. Those risks do have a huge psychological impact on the families of the patients. But we have to take them instead of waiting for when the accurate cure for the problem will be available. There are a few advantages of PGD which makes it an important process while conducting it with an IVF process. The advantages are mentioned below.

·         It’s a great alternative for prenatal diagnostic testing: A lot of couples now opt for it to avoid the distress which is closely associated with the diagnosis.

·         An alternative for termination of pregnancy: If a genetic abnormality is found while parental testing, the parents have very limited options. Either they have to go for a pregnancy termination or they have to give birth to a child with a genetic condition. This is a very difficult decision to take but can be eliminated easily if the PGD is done before the pregnancy begins.

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Author Signature :



The author write the content on the behalf of best IVF Treatment Clinic Indo Nippon IVF in Mumbai Owned By Dr. Goral Gandhi.


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Dr Gautam

IndoNippon IVF World is a leading IVF Clinic in Mumbai from last 25 years. Gautam N. Allahbadia, is the Medical Director of Indo Nippon IVF which is located at Bandra, Mumbai. ..


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